Unlike that induced within an experiment.

‘We wanted to see whether the same applied to the clinical discomfort suffered by people with conditions like arthritis, as no direct comparisons of experimental and scientific pain had been undertaken in the same band of patients.’ Six female and six male sufferers with osteoarthritis of the knee underwent PET brain-scanning during three different pain states: arthritic knee pain, experimental knee pain and a pain-free state. ‘We believed that arthritic and acute experimental pain would be processed within the same areas of the discomfort matrix,’ Dr Kulkarni continued.‘In nearly all patients, the first indication that something is incorrect is finding a recognised tumour, which oftentimes is difficult to take care of’ Associate Professor Tarlinton stated. ‘Now that we realize B-cell lymphoma can be suppressed by the disease fighting capability, we could utilize this information to build up a diagnostic check that identifies people in first stages of this disease, before tumours develop plus they progress to malignancy. There already are therapies that could remove these ‘aberrant’ B cells in at-risk patients, therefore once a check is developed it could be moved towards medical use rapidly.