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Approximately 20 per cent of pupils per course could be labelled as risky. Researchers will invite children aged 13-16 from 9-12 mixed comprehensive schools in Bath, Bristol, Nottingham and Swindon to full a screening questionnaire. The HTA program is a programme of the National Institute for Health Analysis and produces top quality research information regarding the performance, costs, and broader effect of health systems for individuals who use, manage and provide treatment in the NHS.. Can cognitive behavioural therapy help defeat depression? The effectiveness of cognitive behavioural therapy for the treatment of depression will be examined by researchers at the University of Bristol as part of the National Institute for Wellness Research Health Technology Assessment programme.