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Alzheimer’s disease The other symptoms that are linked to the disease are:the personality of the affected person changes instantly and this is common at the onset of the disease; the affected person is usually dominated by sadness, agitation confusion and fear, on till dawn mostly in the evenings and sometimes it goes. This condition is called Sundowner Syndrome. The affected people also find it hard to cope with changes that happen in life; they seclude themselves from activities that involve people and they get disinterested in the family and even friends finally. As the disease progresses, the person will demand more assistance and support in order to make him/her cope in life.