Alzheimer’s may progress more rapidly in people who have high blood circulation pressure or atrial fibrillation Alzheimer’s disease may progress quicker in people with high blood pressure or a form of irregular heartbeat, atrial fibrillation, according to results of a Johns Hopkins study published in the Nov. 6, 2007, problem of Neurology tadalafil tablets 20 mg read more . The findings suggest that treating these conditions may also slow memory reduction in people who have AD. While current medicines for Alzheimer’s disease are effective for some patients in slowing the rate of Advertisement progression, many patients usually do not benefit from the treatments or cannot tolerate them, says lead researcher Michelle M. Mielke, Ph.D., of the Section of Psychiatry and Behavioral Sciences at The Johns Hopkins University College of Medicine.
Dr. Alvarez foresees alpha arrestins becoming a big participant in the refining of such initiatives. ‘Just as has been found out with beta blockers and beta arrestin, I expect we'll find drugs that also have significant alpha arrestin results,’ he says. ‘I really believe that targeting alpha arrestins allows us to develop compounds that are far better and have reduced side effects,’ says Dr. Alvarez.. Alpha arrestins may play a role in cell signaling that is crucial to new drug development A newly found knowledge of receptor signaling may have revealed an easier way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that’s imperative to new drug development.