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Dr. Alvarez foresees alpha arrestins becoming a big participant in the refining of such initiatives. ‘Just as has been found out with beta blockers and beta arrestin, I expect we'll find drugs that also have significant alpha arrestin results,’ he says. ‘I really believe that targeting alpha arrestins allows us to develop compounds that are far better and have reduced side effects,’ says Dr. Alvarez.. Alpha arrestins may play a role in cell signaling that is crucial to new drug development A newly found knowledge of receptor signaling may have revealed an easier way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that’s imperative to new drug development.